验证数据展示
产品信息
16508-1-PBS targets GLIPR2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag9725 Product name: Recombinant human GLIPR2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-90 aa of BC017918 Sequence: MGKSASKQFHNEVLKAHNEYRQKHGVPPLKLCKNLNREAQQYSEALASTRILKHSPESSRGQCGENLAWASYDQTGKEVADRWYSEVHFM 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | GLI pathogenesis-related 2 |
| 别名 | Glioma pathogenesis-related protein 2, GLI pathogenesis related 2, GAPR-1, GAPR1, GAPR 1 |
| 计算分子量 | 153aa,17 kDa; 90aa,10 kDa |
| 观测分子量 | 17 kDa |
| GenBank蛋白编号 | BC017918 |
| 基因名称 | GLIPR2 |
| Gene ID (NCBI) | 152007 |
| RRID | AB_3669246 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H4G4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Golgi-associated plant pathogenesis-related protein 1 (GLIPR2, also known as C9orf19 and GAPR1) is a multifunctional protein with dual engagement in normal cellular processes and the intricacies of cancer biology. GLIPR2 has also been associated with a spectrum of cellular functions encompassing the regulation of autophagy (PMID: 12137952; 18824526). It has been reported that GLIPR2 is a newly identified negative regulator of autophagy that inhibits the class III phosphatidylinositol 3-kinase complex I (PtdIns3K-C1) complex activity (PMID: 33222586).



