GDF10 Monoclonal antibody, PBS Only

GDF10 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66371-1-PBS

产品说明书

CloneNo. 1B7D12

宿主/亚型

Mouse / IgG2a

种属反应性

human, pig, rat

应用

WB, Indirect ELISA

BIP, BMP 3b, BMP3B, Bone inducing protein, Bone morphogenetic protein 3B, GDF 10, GDF10

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

66371-1-PBS targets GDF10 in WB, Indirect ELISA applications and shows reactivity with human, pig, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, pig, rat
免疫原 GDF10 fusion protein Ag4906 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 growth differentiation factor 10
别名 BIP, BMP 3b, BMP3B, Bone inducing protein, Bone morphogenetic protein 3B, GDF 10, GDF10
计算分子量 53 kDa
观测分子量 53 kDa
GenBank蛋白编号BC028237
基因名称 GDF10
Gene ID (NCBI) 2662
RRIDAB_2881750
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP55107
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Growth differentiation factor-10 (GDF10), also known as BMP3b, is a member of the transforming growth factor-b (TGF-b) superfamily. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. GDF10 plays a role in head formation and may have multiple roles in skeletal morphogenesis. Additionally, GDF10 may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer.

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