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验证数据展示

  • WB analysis using 13940-1-AP (same clone as 13940-1-PBS)

    WB analysis using 13940-1-AP (same clone as 13940-1-PBS)

    Boiled and 37°C incubated mouse brain tissue were subjected to SDS PAGE followed by western blot with 13940-1-AP (GABA B receptor 1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13940-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 13940-1-AP (same clone as 13940-1-PBS)

    IHC staining of rat brain using 13940-1-AP (same clone as 13940-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 13940-1-AP (GABA B receptor 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13940-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 13940-1-AP (same clone as 13940-1-PBS)

    IHC staining of mouse brain using 13940-1-AP (same clone as 13940-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13940-1-AP (GABA B receptor 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13940-1-PBS in a different storage buffer formulation.

GABA B receptor 1 Polyclonal antibody, PBS Only

GABA B receptor 1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 13940-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

GABAB receptor 1, GABBR1, GABA B R1, GABA BR1, GABA-B receptor 1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

13940-1-PBS targets GABA B receptor 1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag4838

Product name: Recombinant human GABBR1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 101-471 aa of BC041332

Sequence: SKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 gamma-aminobutyric acid (GABA) B receptor, 1
别名 GABAB receptor 1, GABBR1, GABA B R1, GABA BR1, GABA-B receptor 1
计算分子量 961 aa, 108 kDa
观测分子量 105-130 kDa
GenBank蛋白编号BC041332
基因名称 GABBR1
Gene ID (NCBI) 2550
RRIDAB_2108159
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UBS5
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GABA B receptor 1 (GABBR1) is an essential protein subunit that forms the functional GABA B receptor, a metabotropic receptor for the primary inhibitory neurotransmitter in the central nervous system, gamma-aminobutyric acid (GABA). Unlike the fast-acting ionotropic GABA A receptors, GABA B receptors mediate slow, prolonged inhibitory signaling through G-proteins. Two bands with the apparent molecular weights of 130 and 105 kDa were corresponding to GABAB1a and GABAB1b proteins, were identified in the brain extract and membrane extract of wild-type mice (PMID: 12970075).

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