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验证数据展示

  • WB analysis using 86913-6-RR (same clone as 86913-6-PBS)

    WB analysis using 86913-6-RR (same clone as 86913-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86913-6-RR (FGA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86913-6-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 86913-6-RR (same clone as 86913-6-PBS)

    IHC staining of human kidney using 86913-6-RR (same clone as 86913-6-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 86913-6-RR (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 86913-6-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 86913-6-RR (same clone as 86913-6-PBS)

    IHC staining of human placenta using 86913-6-RR (same clone as 86913-6-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 86913-6-RR (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 86913-6-PBS in a different storage buffer formulation.

Fibrinogen Alpha Chain Recombinant monoclonal antibody, PBS Only

Fibrinogen Alpha Chain Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 86913-6-PBS

产品说明书

CloneNo. 260891B12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

FGA, Fib2, Fibrinopeptide A

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86913-6-PBS targets Fibrinogen Alpha Chain in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag33674

Product name: Recombinant human FGA protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 20-218 aa of BC020764

Sequence: ADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSGEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVTANNLLVARVTTEETPHLKARAIKWQMRPEVKPIMKEHIAPREAMLNLALSEVSTLLLWGSLPCPPRLS*

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 fibrinogen alpha chain
别名 FGA, Fib2, Fibrinopeptide A
计算分子量 866 aa, 95 kDa
观测分子量95kDa, 70 kDa
GenBank蛋白编号BC020764
基因名称 Fibrinogen Alpha Chain
Gene ID (NCBI) 2243
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP02671
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGA is the alpha chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide A is cleaved from FGA by thrombin.

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