FceR1a Recombinant antibody

FceR1a Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 84662-3-RR

产品说明书

CloneNo. 241848D1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

FceRIa, FcERI, Fc-epsilon RI-alpha, FCE1A, Fc epsilon RI alpha

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inhuman testis tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84662-3-RR targets FceR1a in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
别名 FceRIa, FcERI, Fc-epsilon RI-alpha, FCE1A, Fc epsilon RI alpha
计算分子量30kDa
观测分子量55-65 kDa
GenBank蛋白编号NM_001387280.1
基因名称 FceR1a
Gene ID (NCBI) 2205
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP12319
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316). The calculated molecular weight of FceR1a is 30 kDa, the 55- to 70-kDa bands detected by this antibody are probably caused by heterogeneous glycosylation (PMID: 11344350; 12671054).

实验方案

Product Specific Protocols
WB protocol for FceR1a antibody 84662-3-RRDownload protocol
Standard Protocols
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