验证数据展示
产品信息
98430-1-PBS targets Fas Ligand/CD178 in FC applications and shows reactivity with rat samples.
经测试应用 | FC Application Description |
经测试反应性 | rat |
免疫原 | Fas Ligand/CD178 fusion protein Eg3218 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | Fas ligand (TNF superfamily, member 6) |
别名 | ADAM10-processed FasL form, APL, Apt1Lg1, CD178, CD95 ligand |
计算分子量 | 31 kDa |
GenBank蛋白编号 | NM_012908.1 |
基因名称 | Faslg |
Gene ID (NCBI) | 25385 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P36940 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD178, also known as Fas ligand, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. It is expressed on NK cells, cytotoxic T lymphocytes and activated CD4+ Th1 cells. CD178 transduces apoptotic signal into cells by binding to FAS/CD95. It is involved as a death factor in the regulation of activation-induced cell death, establishment of immune privilege and tumor cell survival.