验证数据展示
经过测试的应用
| Positive IF/ICC detected in | HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-84672-2 targets FSTL1 in IF/ICC applications and shows reactivity with human samples.
| 经测试应用 | IF/ICC Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag33795 Product name: Recombinant human FSTL1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-308 aa of BC000055 Sequence: MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKTKRVSTKEI 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | follistatin-like 1 |
| 别名 | 241900D8, follistatin like 1, Follistatin like protein 1, Follistatin related protein 1, Follistatin-like protein 1 |
| 计算分子量 | 308 aa, 35 kDa |
| GenBank蛋白编号 | BC000055 |
| 基因名称 | FSTL1 |
| Gene ID (NCBI) | 11167 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q12841 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Follistatin-like protein 1 (FSTL1) is a secreted glycoprotein predominantly produced by mesenchymal cells. It is highly expressed during tissue fibrosis and plays a significant role in various pathological conditions, including inflammation, fibrosis, and immune regulation. It functions as a matricellular protein, interacting with extracellular matrix components and modulating cell-matrix interactions. FSTL1 is involved in multiple biological processes, such as cell proliferation, apoptosis, metabolism, differentiation, and immune response.
