验证数据展示
产品信息
15936-1-AP targets FRK in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | FRK fusion protein Ag10024 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | fyn-related kinase |
| 别名 | FRK, fyn related kinase, GTK, Protein tyrosine kinase 5, PTK5, RAK, Tyrosine protein kinase FRK |
| 计算分子量 | 505 aa, 56 kDa |
| GenBank蛋白编号 | BC012916 |
| 基因名称 | FRK |
| Gene ID (NCBI) | 2444 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P42685 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The fyn-related kinase (FRK) belongs to the tyrosine kinase family of protein kinases and is also named as PTK5(protein-tyrosine kinase 5), RAK(Nuclear tyrosine protein kinase). The Frk is a tyrosine kinase expressed in various tissues, such as the gastrointestinal tract and pancreatic islet cells. It affects pancreatic beta cell number during embryogenesis and promotes beta cell cytotoxic signals in response to streptozotocin(PMID:20157399). It may function as a tumor suppressor(PMID:19345329).