验证数据展示
产品信息
34275-1-PBS targets FOXD2 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag41978 Product name: Recombinant human FOXD2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 11-100 aa of NM_004474.4 Sequence: MSSESSPAALSEADADIDVVGGGSGGGELPARSGPRAPRDVLPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPG 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | forkhead box D2 |
| 别名 | FKHL17, Forkhead box protein D2, Forkhead-related protein FKHL17, Forkhead-related transcription factor 9, FREAC9 |
| 计算分子量 | 49kDa，495aa |
| 观测分子量 | 51 kDa |
| GenBank蛋白编号 | NM_004474.4 |
| 基因名称 | FOXD2 |
| Gene ID (NCBI) | 2306 |
| RRID | AB_3743182 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | O60548 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FOXD2, as one descendant of the FOX gene family, has been mentioned in many articles to show a high expression in several cancers. FOXD2 showed a high expression in gastric adenocarcinoma tissues and cells, and silencing FOXD2 could hinder gastric adenocarcinoma cell proliferation. In addition, FOXD2 could facilitate gastric adenocarcinoma cell proliferation by activating the expression of its downstream gene IQGAP3 and increasing intracellular Ca2+ concentration (PMID: 37724892).
