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验证数据展示

  • FC experiment of Transfected HEK-293T using 98244-1-RR

    FC experiment of Transfected HEK-293T using 98244-1-RR

    1x10^6 HEK-293T cells or FGFR2/CD332 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human FGFR2/CD332 Rabbit Recombinant Antibody (98244-1-RR, Clone: 241383D11) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed.

  • FC experiment of Transfected HEK-293T using 98244-1-RR

    FC experiment of Transfected HEK-293T using 98244-1-RR

    1x10^6 HEK-293T cells (left) or FGFR2/CD332 transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Human FGFR2/CD332 Rabbit Recombinant Antibody (98244-1-RR, Clone:241383D11) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98244-1-RR

    Affinity and Kinetic Characterization of 98244-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98244-1-RR against Human FGFR2/CD332 were performed. The affinity constant is 1.69 nM.

Anti-Human FGFR2/CD332 Rabbit Recombinant Antibody

FGFR2/CD332 Recombinant Antibody for FC
Cat No. 98244-1-RR

产品说明书

CloneNo. 241383D11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

FGFR2, CFD1, CEK3, CD332, BFR 1

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive FC detected inTransfected HEK-293T cells

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98244-1-RR targets FGFR2/CD332 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 fibroblast growth factor receptor 2
别名 FGFR2, CFD1, CEK3, CD332, BFR 1
计算分子量92kd
GenBank蛋白编号NM_000141.4
基因名称 FGFR2
Gene ID (NCBI) 2263
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP21802
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

FGFR2 (Fibroblast growth factor receptor 2), also known as CD332, is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration, and apoptosis. Ligand binding leads to the activation of several signaling pathways, such as RAS, MAPK1/ERK2, MAPK3/ERK1, and the MAP Kinase signaling pathway, as well as the AKT1 signaling pathway. Mutations in the gene of FGFR2 are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis.

实验方案

Product Specific Protocols
FC protocol for FGFR2/CD332 antibody 98244-1-RRDownload protocol
Standard Protocols
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