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验证数据展示

  • IP experiment of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

    IP experiment of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

    IP result of anti-FGFR1 (IP:30358-1-AP, 4ug; Detection:30358-1-AP 1:300) with SH-SY5Y cells lysate 770 ug. This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

    IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

    IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 30358-1-AP (same clone as 30358-1-PBS)

    IHC staining of mouse brain using 30358-1-AP (same clone as 30358-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

  • IHC staining of rat kidney using 30358-1-AP (same clone as 30358-1-PBS)

    IHC staining of rat kidney using 30358-1-AP (same clone as 30358-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

    IF Staining of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using FGFR1 antibody (30358-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

FGFR1 Polyclonal antibody, PBS Only

FGFR1 Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA
Cat No. 30358-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, IF/ICC, IP, Indirect ELISA

别名

bFGF R 1, BFGFR, bFGF-R-1, CD331, CEK

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

30358-1-PBS targets FGFR1 in IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 fibroblast growth factor receptor 1
别名 bFGF R 1, BFGFR, bFGF-R-1, CD331, CEK
计算分子量 820 aa, 91 kDa
观测分子量80 kDa, 95 kDa, 105 kDa
GenBank蛋白编号BC018128
基因名称 FGFR1
Gene ID (NCBI) 2260
RRIDAB_3669716
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP11362
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processes including embryonic development, cell proliferation, differentiation, migration, and tumorigenesis. Mutations in the FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer, and autosomal dominant Kallmann syndrome. Alternatively spliced variants that encode different protein isoforms have been described.

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