FGFR1 Polyclonal antibody
FGFR1 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA and More (2)
Conjugate
Unconjugated
验证数据展示
发表文章中的应用
| WB | See 1 publications below |
| IHC | See 1 publications below |
产品信息
12947-1-AP targets FGFR1 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA |
| Cited Applications | WB, IHC |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Immunogen | FGFR1 fusion protein Ag3646 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | fibroblast growth factor receptor 1 |
| Synonyms | bFGF R 1, BFGFR, CD331, CEK, FGFBR, FGFR 1, FGFR1, FLG, FLT 2, FLT2, Fms like tyrosine kinase 2, HBGFR, KAL2, N SAM, OGD, Proto oncogene c Fgr |
| Calculated Molecular Weight | 820 aa, 91 kDa |
| GenBank Accession Number | BC018128 |
| Gene Symbol | FGFR1 |
| Gene ID (NCBI) | 2260 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P11362 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processed including embryonic development, cell proliferation, differentiation, migration, and tumorigenesis. Mutations in FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome. Alternatively spliced variants which encode different protein isoforms have been described.
发表文章
| Species | Application | Title |
|---|---|---|
Oral Dis Fibroblast growth factor receptor 1 and 4 combined with lymph node metastasis predicts poor prognosis in oral cancer |