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FAM96A Polyclonal antibody, PBS Only

FAM96A Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA
Cat No. 20776-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IF/ICC, IP, Indirect ELISA

CIA2A, CIAO2A, Cytosolic iron-sulfur assembly component 2A, MIP18 family protein FAM96A, Protein FAM96A

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存


产品信息

20776-1-PBS targets FAM96A in IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag14770

Product name: Recombinant human FAM96A protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-90 aa of BC008865

Sequence: MQRVSGLLSWTLSRVLWLSGLSEPGAARQPRIMEEKALEVYDLIRTIRDPEKPNTLEELEVVSESCVEVQEINEEEYLVIIRFTPTVPHC

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 family with sequence similarity 96, member A
别名 CIA2A, CIAO2A, Cytosolic iron-sulfur assembly component 2A, MIP18 family protein FAM96A, Protein FAM96A
计算分子量 160 aa, 18 kDa
观测分子量18-21 kDa
GenBank蛋白编号BC008865
基因名称 FAM96A
Gene ID (NCBI) 84191
RRIDAB_3669346
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H5X1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FAM96A (family with sequence similarity 96, member A), also called cytosolic iron-sulfur assembly component 2A (CIAO2A), a recently identified member of the cytosolic iron-sulfur (Fe/S) protein assembly machinery and regulator of cellular iron homeostasis, is a novel pro-apoptotic APAF1-binding protein facilitating the effective induction of cell death via the mitochondrial apoptosis pathway. FAM96A is substantially enriched in macrophages comprised primarily of a DUF59 domain (residues 31-157) and an N-terminal signal peptide (residues 1-27), that is expressed at low levels in tumor cells (PMID: 29399066).

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