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CoraLite®555-conjugated FAH Monoclonal antibody

FAH Monoclonal Antibody for IF/ICC

Host / Isotype

Mouse / IgG1

Reactivity

Human, pig, rat, mouse

Applications

IF/ICC

Conjugate

CoraLite®555 Fluorescent Dye

CloneNo.

2F8E11

Cat No : CL555-67986

Print datasheet

Synonyms

Beta diketonase, FAA, FAH, Fumarylacetoacetase, Fumarylacetoacetate hydrolase

验证数据展示

  • IF Staining of HepG2 using CL555-67986

    IF Staining of HepG2 using CL555-67986

    Immunofluorescent analysis of (-20°C Methanol) fixed HepG2 cells using CoraLite®555 FAH antibody (CL555-67986, Clone: 2F8E11 ) at dilution of 1:200.

经过测试的应用

Positive IF detected inHepG2 cells
For other applications, we recommend the unconjugated version of this antibody, 67986-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL555-67986 targets FAH in IF applications and shows reactivity with Human, pig, rat, mouse samples.

Tested Applications IF/ICC
Tested Reactivity Human, pig, rat, mouse
Immunogen FAH fusion protein Ag6704 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name fumarylacetoacetate hydrolase (fumarylacetoacetase)
Synonyms Beta diketonase, FAA, FAH, Fumarylacetoacetase, Fumarylacetoacetate hydrolase
Calculated Molecular Weight 46 kDa
Observed Molecular Weight 40-45 kDa
GenBank Accession NumberBC002527
Gene Symbol FAH
Gene ID (NCBI) 2184
Conjugate CoraLite®555 Fluorescent Dye
Excitation/Emission Maxima Wavelengths557 nm / 570nm
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP16930
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FAH is also named as FAA(fumarylacetoacetase), the last enzyme in tyrosine degradation, functionally important in the liver and kidney(PMID:8473520). FAH is a metabolic enzyme catalyzing the last step of tyrosine and phenylalanine catabolism: the hydrolysis of fumarylacetoacetate into acetoacetate and fumarate. In humans, deficiency of this activity is associated with the metabolic disease hereditary tyrosinaemia type I, which is also known as hepatorenal tyrosinaemia(PMID:17768357).

实验方案

Product Specific Protocols
IF protocol for CL555 FAH antibody CL555-67986Download protocol
Standard Protocols
Click here to view our Standard Protocols