验证数据展示
产品信息
55080-1-PBS targets Ephrin B3 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ephrin-B3 |
| 别名 | EFNB3, EFL6, EPLG8, LERK 8, LERK8 |
| 计算分子量 | 36 kDa |
| 观测分子量 | 45-50 kDa |
| GenBank蛋白编号 | NM_001406 |
| 基因名称 | EFNB3 |
| Gene ID (NCBI) | 1949 |
| RRID | AB_3743199 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q15768 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Ephrin-B3 is a transmembrane ligand that binds primarily to EphB receptors to mediate bidirectional cell signaling, crucial for neural development, axon guidance, and synaptic plasticity. Highly expressed in the brain and spinal cord, it acts as a midline repellent to guide axonal pathfinding (PMID: 16951161). Ephrin‑B3 is important in the regulation of cell proliferation, differentiation and migration via cell‑cell contact, and can activate the reelin pathway during brain development. The band of ephrin-B3 was identical to phosphorylated ephrin-B at 50 kDa (PMID: 16951161, 21447033).
