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验证数据展示

  • WB analysis of A549 using 67477-1-Ig (same clone as 67477-1-PBS)

    WB analysis of A549 using 67477-1-Ig (same clone as 67477-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

  • WB analysis using 67477-1-Ig (same clone as 67477-1-PBS)

    WB analysis using 67477-1-Ig (same clone as 67477-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

ERAP2 Monoclonal antibody, PBS Only

ERAP2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67477-1-PBS

产品说明书

CloneNo. 2B11A2

宿主/亚型

Mouse / IgG2b

种属反应性

Human, Rat

应用

WB, Indirect ELISA

别名

ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

67477-1-PBS targets ERAP2 in WB, Indirect ELISA applications and shows reactivity with Human, Rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, Rat
免疫原

CatNo: Ag30061

Product name: Recombinant human ERAP2 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 41-180 aa of BC065240

Sequence: PSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY

种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 endoplasmic reticulum aminopeptidase 2
别名 ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP
计算分子量 110 kDa
观测分子量 110-120 kDa
GenBank蛋白编号BC065240
基因名称 ERAP2
Gene ID (NCBI) 64167
RRIDAB_2882704
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ6P179
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ERAP2(Endoplasmic reticulum aminopeptidase 2) is also named as LRAP(Leukocyte-derived arginine aminopeptidase). It plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. ERAP2 can form heterodimers with ERAP1(PMID:15908954). Defects in the expression of ERAP2 may cause improper antigen processing, possibly leading to favor tumor escape from the immune surveillance. ERAP2 has the calculated molecular mass of 105-110 kDa, and apparent molecular mass of 120 kDa duo to the glycosylation.