验证数据展示
产品信息
67477-1-PBS targets ERAP2 in WB, Indirect ELISA applications and shows reactivity with Human, Rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, Rat |
免疫原 | ERAP2 fusion protein Ag30061 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | endoplasmic reticulum aminopeptidase 2 |
别名 | ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP |
计算分子量 | 110 kDa |
观测分子量 | 110-120 kDa |
GenBank蛋白编号 | BC065240 |
基因名称 | ERAP2 |
Gene ID (NCBI) | 64167 |
RRID | AB_2882704 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q6P179 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ERAP2(Endoplasmic reticulum aminopeptidase 2) is also named as LRAP(Leukocyte-derived arginine aminopeptidase). It plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. ERAP2 can form heterodimers with ERAP1(PMID:15908954). Defects in the expression of ERAP2 may cause improper antigen processing, possibly leading to favor tumor escape from the immune surveillance. ERAP2 has the calculated molecular mass of 105-110 kDa, and apparent molecular mass of 120 kDa duo to the glycosylation.