ERAP2 Monoclonal antibody, PBS Only

ERAP2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67477-1-PBS

产品说明书

CloneNo. 2B11A2

宿主/亚型

Mouse / IgG2b

种属反应性

Human, Rat

应用

WB, Indirect ELISA

ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

67477-1-PBS targets ERAP2 in WB, Indirect ELISA applications and shows reactivity with Human, Rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, Rat
免疫原 ERAP2 fusion protein Ag30061 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 endoplasmic reticulum aminopeptidase 2
别名 ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP
计算分子量 110 kDa
观测分子量 110-120 kDa
GenBank蛋白编号BC065240
基因名称 ERAP2
Gene ID (NCBI) 64167
RRIDAB_2882704
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ6P179
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ERAP2(Endoplasmic reticulum aminopeptidase 2) is also named as LRAP(Leukocyte-derived arginine aminopeptidase). It plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. ERAP2 can form heterodimers with ERAP1(PMID:15908954). Defects in the expression of ERAP2 may cause improper antigen processing, possibly leading to favor tumor escape from the immune surveillance. ERAP2 has the calculated molecular mass of 105-110 kDa, and apparent molecular mass of 120 kDa duo to the glycosylation.

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