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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 85184-5-RR (same clone as 85184-5-PBS)

    WB analysis using 85184-5-RR (same clone as 85184-5-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 85184-5-RR (EPS8 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85184-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85184-5-RR

    Affinity and Kinetic Characterization of 85184-5-RR

    Biolayer interferometry (BLl) kinetic assays of 85184-5-RR against Human EPS8 were performed. The affinity constant is 27.9 nM.

EPS8 Recombinant antibody, PBS Only

EPS8 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85184-5-PBS

产品说明书

CloneNo. 242835G12

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

Epidermal growth factor receptor kinase substrate 8

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy EPS8 Ready-To-Use IHC Kit. EPS8 primary antibody included.

产品信息

85184-5-PBS targets EPS8 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 EPS8 fusion protein Ag3121 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 epidermal growth factor receptor pathway substrate 8
别名 Epidermal growth factor receptor kinase substrate 8
计算分子量 822 aa, 92 kDa
观测分子量 97 kDa
GenBank蛋白编号BC030010
基因名称 EPS8
Gene ID (NCBI) 2059
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ12929
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Epidermal growth factor receptor Pathway Substrate 8 (EPS8) is a crucial regulator of the actin cytoskeleton dynamics accompanying cell motility and invasion. This protein contains one PH domain and one SH3 domain leading to its binding activity with multiple cellular targets. EPS8 can function as a unique actin capping protein specifically required for dendritic cell migration and plays roles in the regulation of axonal filopodia in neuronal development and synapse formation. The EPS8 gene may contribute to the development of a subset of colorectal cancers and could have applications in diagnosis and treatment.