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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
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验证数据展示

  • FC experiment of bEnd.3 using 98248-1-RR (same clone as 98248-1-PBS)

    FC experiment of bEnd.3 using 98248-1-RR (same clone as 98248-1-PBS)

    1x10^6 bEnd.3 cells were surface stained with 0.25 ug Anti-Mouse EPCR/CD201 Rabbit Recombinant Antibody (98248-1-RR, Clone: 241853A7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98248-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98248-1-RR

    Affinity and Kinetic Characterization of 98248-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98248-1-RR against Mouse EPCR/CD201 were performed. The affinity constant is 52.5 pM.

Anti-Mouse EPCR/CD201 Rabbit Recombinant Antibody, PBS Only

EPCR/CD201 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98248-1-PBS

产品说明书

CloneNo. 241853A7

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

Centrosomal protein CCD41, Centrocyclin, CD201, APC receptor, Activated protein C receptor

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98248-1-PBS targets EPCR/CD201 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 protein C receptor, endothelial
别名 Centrosomal protein CCD41, Centrocyclin, CD201, APC receptor, Activated protein C receptor
计算分子量27kDa
GenBank蛋白编号NM_011171.2
基因名称 PROCR
Gene ID (NCBI) 19124
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ64695
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EPCR, also known as CD201, protein C receptor (PROCR), or activated protein C receptor (APC receptor), is a transmembrane glycoprotein. EPCR promotes the activation of protein C, which has anticoagulant and cytoprotective effects. EPCR facilitates the activation of protein C by the thrombin-thrombomodulin complex but also facilitates APC-mediated cytoprotective effects on cells that involve the activation of protease-activated receptors (PAR) 1 and 3(PMID: 27207424).