验证数据展示
产品信息
32226-1-PBS targets ENPP7 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag36493 Product name: Recombinant human ENPP7 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 150-400 aa of NM_178543.4 Sequence: QGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPE 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ectonucleotide pyrophosphatase/phosphodiesterase 7 |
| 别名 | Alkaline sphingomyelin phosphodiesterase, Alk-SMase, EC:3.1.4.12, Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, E-NPP 7 |
| 计算分子量 | 51 kDa，458aa |
| 观测分子量 | 51 kDa |
| GenBank蛋白编号 | NM_178543.4 |
| 基因名称 | ENPP7 |
| Gene ID (NCBI) | 339221 |
| RRID | AB_3742548 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q6UWV6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7) stands out as an alkaline sphingomyelinase that functions in the intestine to cleave sphingomyelin (SM) into ceramide and phosphocholine in a phospholipase C (PLC) -like manner and has been associated with hepatobiliary diseases. Reduced ENPP7 activity is detected in colorectal cancer and in familial adenomatous polyposis, suggesting a link between decreased SM metabolism and colon tumorigenesis (PMID: 22177013; 28292932).
