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验证数据展示

  • WB analysis using 83468-6-RR (same clone as 83468-6-PBS)

    WB analysis using 83468-6-RR (same clone as 83468-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83468-6-RR (ELAC2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83468-6-PBS in a different storage buffer formulation.

  • WB analysis of MCF-7 using 83468-6-RR (same clone as 83468-6-PBS)

    WB analysis of MCF-7 using 83468-6-RR (same clone as 83468-6-PBS)

    WB result of ELAC2 antibody (83468-6-RR; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-ELAC2 transfected MCF-7 cells. This data was developed using the same antibody clone with 83468-6-PBS in a different storage buffer formulation.

  • FC experiment of A431 using 83468-6-RR (same clone as 83468-6-PBS)

    FC experiment of A431 using 83468-6-RR (same clone as 83468-6-PBS)

    1x10^6 A431 cells were intracellularly stained with 0.25 ug ELAC2 Recombinant antibody (83468-6-RR, Clone:240487B6) and APC-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011). This data was developed using the same antibody clone with 83468-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83468-6-RR

    Affinity and Kinetic Characterization of 83468-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83468-6-RR against Human ELAC2 were performed. The affinity constant is below 1 pM.

  • Featured Product
  • KD/KO验证

ELAC2 Recombinant antibody, PBS Only

ELAC2 Uni-rAbTM Recombinant Antibody for WB, FC (Intra), ELISA
Cat No. 83468-6-PBS

产品说明书

CloneNo. 240487B6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, FC (Intra), ELISA

别名

240487B6, EC:3.1.26.11, elaC homolog 2 (E. coli), ElaC homolog protein 2, ELC2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy ELAC2 Ready-To-Use IHC Kit. ELAC2 primary antibody included.

产品信息

83468-6-PBS targets ELAC2 in WB, FC (Intra), ELISA applications and shows reactivity with human samples.

经测试应用 WB, FC (Intra), ELISA Application Description
经测试反应性 human
免疫原 ELAC2 fusion protein Ag0105 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 elaC homolog 2 (E. coli)
别名 240487B6, EC:3.1.26.11, elaC homolog 2 (E. coli), ElaC homolog protein 2, ELC2
计算分子量 92 kDa
观测分子量 97 kDa
GenBank蛋白编号BC004158
基因名称 ELAC2
Gene ID (NCBI) 60528
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ9BQ52
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Putative prostate cancer susceptibility protein (ELAC2) is encoded by HPC2/ELAC2 gene. HPC2 is a potential prostate cancer predisposition gene playing a role in genetic susceptibility to prostate cancer.It is a zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity and probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.Defects in ELAC2 may be a cause of susceptibility to prostate cancer (PC).