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验证数据展示

  • WB analysis of human brain using 60257-1-Ig (same clone as 60257-1-PBS)

    WB analysis of human brain using 60257-1-Ig (same clone as 60257-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 60257-1-Ig (Dynamitin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

  • IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas slide using 60257-1-Ig (Dynamitin antibody at dilution of 1:50. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with DCTN2 antibody included
  • IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas slide using 60257-1-Ig (Dynamitin antibody at dilution of 1:50. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with DCTN2 antibody included

Dynamitin (1-401 AA) Monoclonal antibody, PBS Only

Dynamitin (1-401 AA) Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60257-1-PBS

产品说明书

CloneNo. 2B9A5

宿主/亚型

Mouse / IgG3

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, Dynamitin, Dynamitin (1-401 AA), p50 dynamitin, RBP50

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy DCTN2 Ready-To-Use IHC Kit. DCTN2 primary antibody included.

产品信息

60257-1-PBS targets Dynamitin (1-401 AA) in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Dynamitin (1-401 AA) fusion protein Ag1902 种属同源性预测
宿主/亚型 Mouse / IgG3
抗体类别 Monoclonal
产品类型 Antibody
全称 dynactin 2 (p50)
别名 DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, Dynamitin, Dynamitin (1-401 AA), p50 dynamitin, RBP50
计算分子量 401 aa, 44 kDa
观测分子量 52+150 kDa
GenBank蛋白编号BC014083
基因名称 Dynamitin
Gene ID (NCBI) 10540
RRIDAB_2881378
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13561
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 86aa of full length p50 dynamitin.