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Dimethylenastron

Dimethylenastron 是一种驱动蛋白Eg5抑制剂，IC50值为 200 nM。它可阻止具有单极纺锤体的细胞，所有染色体都以单极纺锤体方式附着在该纺锤体上。

CAS号

863774-58-7

分子式

C16H18N2O2S

主要靶点

Kinesin

仅限科研使用

Cat No : CM04931

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Synonyms

验证数据展示

  • CAS No.: 863774-58-7

    Dimethylenastron
    CAS#: 863774-58-7

产品信息

Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.

CAS号 863774-58-7
分子式 C16H18N2O2S
主要靶点 Kinesin
主要通路 细胞骨架
分子量 302.39
纯度 98.07%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

靶点活性

Eg5:200 nM.

体外活性

Dimethylenastron (DMN) inhibits the growth of LECs and HUVECs in a dose- and time-dependent manner.

溶解度

DMSO:31 mg/mL

参考文献

1.Aljaberi AM, et al. Cell Cycle. 2015;14(11):1738-47.
2.Exertier P, et al. Oncotarget. 2013 Dec;4(12):2302-16.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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