×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 21979-1-AP (same clone as 21979-1-PBS)

    WB analysis using 21979-1-AP (same clone as 21979-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21979-1-AP (DYRK2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21979-1-PBS in a different storage buffer formulation.

  • IF Staining of K-562 using 21979-1-AP (same clone as 21979-1-PBS)

    IF Staining of K-562 using 21979-1-AP (same clone as 21979-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed K-562 cells using DYRK2 antibody (21979-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 21979-1-PBS in a different storage buffer formulation.

DYRK2 Polyclonal antibody, PBS Only

DYRK2 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 21979-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

Dual specificity tyrosine-phosphorylation-regulated kinase 2, DYRK 2, EC:2.7.12.1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy DYRK2 Ready-To-Use IHC Kit. DYRK2 primary antibody included.

产品信息

21979-1-PBS targets DYRK2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag13480

Product name: Recombinant human DYRK2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-300 aa of BC006375

Sequence: MLTRKPSAAAPAAYPTGRGGDSAVRQLQASPGLGAGATRSGVGTGPPSPIALPPLRASNAAAAAHTIGGSKHTMNDHLHVGSHAHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLDSIHRRQGSSTSLKSMEGMGKVKATPMTPEQAMKQYMQKLTAFEHHEIFSYPEIYFLGLNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
别名 Dual specificity tyrosine-phosphorylation-regulated kinase 2, DYRK 2, EC:2.7.12.1
计算分子量 67 kDa
观测分子量67~70 kDa
GenBank蛋白编号BC006375
基因名称 DYRK2
Gene ID (NCBI) 8445
RRIDAB_3742061
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ92630
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DYRK (Dual-specificity tyrosine phosphorylation-regulated kinase 2) is the only member of the Dual-specificity tYrosine phosphorylation-Regulated Kinase (DYRK) family that functions as a kinase activity-independent scaffold for an E3 ubiquitin ligase complex (PMID: 33376136). DYRK2 is involved in cell survival, development, differentiation, gene transcription, proteasomal regulation, and microtubule formation. DYRK2 is a key regulator of cell cycle and apoptosis in response to DNA damage via phosphorylation of p53. DYRK2 has two isoforms and is mostly localized in the cytoplasm; however, it accumulates in the nucleus under genotoxic stress conditions (PMID: 31505048, 37886981).

||
New chat

Able™

正在加载，请稍候...