验证数据展示
Planning an IHC experiment? We recommend our IHCeasy DYNLT1 Ready-To-Use IHC Kit. DYNLT1 primary antibody included.
产品信息
68312-1-PBS targets DYNLT1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | Human, mouse, rat |
| 免疫原 | DYNLT1 fusion protein Ag33072 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | dynein, light chain, Tctex-type 1 |
| 别名 | CW 1, DYNLT1, Protein CW 1, TCTEL1, tctex 1, TCTEX1 |
| 计算分子量 | 113 aa, 12 kDa |
| 观测分子量 | 12 kDa |
| GenBank蛋白编号 | BC029412 |
| 基因名称 | DYNLT1 |
| Gene ID (NCBI) | 6993 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P63172 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DYNLT (or Tctex-1) was originally described as a light chain component of the dynein motor complex. Tctex-1 also has several dynein-independent functions, including roles in G protein signaling activation and neuronal growth. Tctex-1 is selectively enriched in proliferating neural progenitors of both embryonic and adult brains. Genetic knockdown of Tctex-1 in radial precursors promoted neurogenesis, indicating its implication in regulation of cortical neurogenesis. (PMID: 19448628)