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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 98273-1-RR (same clone as 98273-1-PBS)

    FC experiment of human PBMCs using 98273-1-RR (same clone as 98273-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human DR5/CD262 Rabbit Recombinant Antibody (98273-1-RR, Clone: 242319H8) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD14. Cells were not fixed. This data was developed using the same antibody clone with 98273-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98273-1-RR (same clone as 98273-1-PBS)

    FC experiment of human PBMCs using 98273-1-RR (same clone as 98273-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human DR5/CD262 Rabbit Recombinant Antibody (98273-1-RR, Clone: 242319H8) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98273-1-PBS in a different storage buffer formulation.

Anti-Human DR5/CD262 Rabbit Recombinant Antibody, PBS Only

DR5/CD262 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98273-1-PBS

产品说明书

CloneNo. 242319H8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

DR5, KILLER/DR5, KILLER, Death receptor 5, CD262

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98273-1-PBS targets DR5/CD262 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 10b
别名 DR5, KILLER/DR5, KILLER, Death receptor 5, CD262
计算分子量 48 kDa
GenBank蛋白编号BC001281
基因名称 DR5
Gene ID (NCBI) 8795
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO14763
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DR5, also known as CD262, TNFRSF10B, TRAILR2, TRICK2 and KILLER, is a widely expressed single-pass type I membrane protein belonging to the tumour necrosis factor receptor superfamily (TNFRSF). It is a receptor for TNF-related apoptosis-inducing ligand (TRAIL), which is a member of the tumor necrosis factor (TNF) family of cytokines and induces apoptosis in a wide variety of cells (PMID: 9311998). DR5 contains two extracellular cysteine-rich repeats, typical for TNF receptor (TNFR) family members, and a cytoplasmic death domain (DD), through which DR5 is capable to transmit the apoptotic signal (PMID: 9311998; 20531300).