• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 98273-1-RR (same clone as 98273-1-PBS)

    FC experiment of human PBMCs using 98273-1-RR (same clone as 98273-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human DR5/CD262 Rabbit RecAb (98273-1-RR, Clone: 242319H8) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD14 Rabbit Recombinant Antibody (CL647-98040, Clone: 230332D7). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98273-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98273-1-RR (same clone as 98273-1-PBS)

    FC experiment of human PBMCs using 98273-1-RR (same clone as 98273-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human DR5/CD262 Rabbit RecAb (98273-1-RR, Clone: 242319H8) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98273-1-PBS in a different storage buffer formulation.

Anti-Human DR5/CD262 Rabbit Recombinant Antibody, PBS Only

DR5/CD262 Recombinant Antibody for FC
Cat No. 98273-1-PBS

产品说明书

CloneNo. 242319H8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

DR5, 242319H8, CD262, Death receptor 5, KILLER

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

98273-1-PBS targets DR5/CD262 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 DR5/CD262 fusion protein Eg1648 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 10b
别名 DR5, 242319H8, CD262, Death receptor 5, KILLER
计算分子量 48 kDa
GenBank蛋白编号BC001281
基因名称 DR5
Gene ID (NCBI) 8795
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDO14763
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DR5, also known as CD262, TNFRSF10B, TRAILR2, TRICK2 and KILLER, is a widely expressed single-pass type I membrane protein belonging to the tumour necrosis factor receptor superfamily (TNFRSF). It is a receptor for TNF-related apoptosis-inducing ligand (TRAIL), which is a member of the tumor necrosis factor (TNF) family of cytokines and induces apoptosis in a wide variety of cells (PMID: 9311998). DR5 contains two extracellular cysteine-rich repeats, typical for TNF receptor (TNFR) family members, and a cytoplasmic death domain (DD), through which DR5 is capable to transmit the apoptotic signal (PMID: 9311998; 20531300).