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验证数据展示

  • WB analysis of Jurkat using 66969-1-Ig (same clone as 66969-1-PBS)

    WB analysis of Jurkat using 66969-1-Ig (same clone as 66969-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66969-1-Ig (DOCK2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66969-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 66969-1-Ig (same clone as 66969-1-PBS)

    IHC staining of human liver cancer using 66969-1-Ig (same clone as 66969-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66969-1-Ig (DOCK2 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66969-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 66969-1-Ig (same clone as 66969-1-PBS)

    IHC staining of human liver cancer using 66969-1-Ig (same clone as 66969-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66969-1-Ig (DOCK2 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66969-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 66969-1-Ig (same clone as 66969-1-PBS)

    IF Staining of HeLa using 66969-1-Ig (same clone as 66969-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using DOCK2 antibody (66969-1-Ig, Clone: 1D7A8 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66969-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

DOCK2 Monoclonal antibody, PBS Only

DOCK2 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66969-1-PBS

产品说明书

CloneNo. 1D7A8

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

dedicator of cytokinesis 2, DOCK2, FLJ46592, KIAA0209

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66969-1-PBS targets DOCK2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 Human
免疫原 DOCK2 fusion protein Ag28582 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 dedicator of cytokinesis 2
别名 dedicator of cytokinesis 2, DOCK2, FLJ46592, KIAA0209
计算分子量 212 kDa, 38 kDa
观测分子量 200-210 kDa
GenBank蛋白编号BC016996
基因名称 DOCK2
Gene ID (NCBI) 1794
RRIDAB_2882291
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ92608
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DOCK2, also named as KIAA0209, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. DOCK2 activates RAC1 and RAC2 small GTPases, probably by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK2 may also participate in IL2 transcriptional activation via the activation of RAC2. The antibody is specific to DOCK2.