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验证数据展示

  • FC experiment of MCF-7 using 98200-1-RR (same clone as 98200-1-PBS)

    FC experiment of MCF-7 using 98200-1-RR (same clone as 98200-1-PBS)

    1x10^6 MCF-7 cells (left) or HeLa cells (right) were surface stained with 0.25 ug Anti-Human DDR1/CD167a Rabbit Recombinant Antibody (98200-1-RR, Clone: 241796D6) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98200-1-PBS in a different storage buffer formulation.

Anti-Human DDR1/CD167a Rabbit Recombinant Antibody, PBS Only

DDR1/CD167a Uni-rAbTM Recombinant Antibody for FC
Cat No. 98200-1-PBS

产品说明书

CloneNo. 241796D6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

DDR1, Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy DDR1 Ready-To-Use IHC Kit. DDR1 primary antibody included.

产品信息

98200-1-PBS targets DDR1/CD167a in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 discoidin domain receptor tyrosine kinase 1
别名 DDR1, Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167
计算分子量101kDa
GenBank蛋白编号NM_001297654.2
基因名称 DDR1
Gene ID (NCBI) 780
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ08345-1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DDR1, or CD167a, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells.