• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IF Staining of HeLa using CL488-84978

    IF Staining of HeLa using CL488-84978

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using CoraLite® Plus 488 Cytokeratin 17-specific antibody (CL488-84978, Clone: 242240A8 ) at dilution of 1:200.

  • IF Staining of HaCaT using CL488-84978

    IF Staining of HaCaT using CL488-84978

    Immunofluorescent analysis of (-20°C Methanol) fixed HaCaT cells using CoraLite® Plus 488 Cytokeratin 17-specific antibody (CL488-84978, Clone: 242240A8 ) at dilution of 1:200.

CoraLite® Plus 488-conjugated Cytokeratin 17-specific Recombinant antibody

Cytokeratin 17-specific Uni-rAbTM Recombinant Antibody for IF/ICC
Cat No. CL488-84978

产品说明书

CloneNo. 242240A8

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IF/ICC

别名

Cytokeratin 17, KRT17, 242240A8, CK 17, CK-17

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive IF/ICC detected inHaCaT cells, HeLa cells
Planning an IHC experiment? We recommend our IHCeasy KRT17 Ready-To-Use IHC Kit. KRT17 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 84978-1-PBS

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-84978 targets Cytokeratin 17-specific in IF/ICC applications and shows reactivity with human, mouse, rat samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse, rat
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 keratin 17
别名 Cytokeratin 17, KRT17, 242240A8, CK 17, CK-17
计算分子量 48 kDa
观测分子量48 kDa
GenBank蛋白编号NM_000422
基因名称 Cytokeratin 17
Gene ID (NCBI) 3872
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ04695
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Keratins are a large family of proteins that form the intermediate filaments that make up the cytoskeleton. Type I keratins are a group of acidic intermediate filament proteins and type II keratins are the basic or neutral counterparts. Keratin 17 is encoded by the KRT17 gene and is a type I cytokeratin found in nail beds, hair follicles, sebaceous glands, and epidermal appendages.The molecular weight of cytokeratin 17 is approximately 49 kDa.Cytokeratin 17 plays a role in the formation and maintenance of epidermal appendages, especially in determining the shape and orientation of hair. It is required for the maintenance of the anagen (growth) state of hair follicles by modulating the function of TNF-alpha for hair cycling and is also involved in tissue repair (PMID: 16702408).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Cytokeratin 17-specific antibody CL488-84978Download protocol
Standard Protocols
Click here to view our Standard Protocols