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验证数据展示

  • IF Staining of HepG2 using CL488-83940-6

    IF Staining of HepG2 using CL488-83940-6

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CoraLite® Plus 488 CXXC5 antibody (CL488-83940-6, Clone: 241034E6 ) at dilution of 1:200.

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CoraLite® Plus 488-conjugated CXXC5 Recombinant monoclonal antibody

CXXC5 Uni-rAb® Recombinant Antibody for IF/ICC
Cat No. CL488-83940-6

产品说明书

CloneNo. 241034E6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC

别名

241034E6, CF5, CXXC finger 5, CXXC-type zinc finger protein 5, HSPC195

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格价格库存

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经过测试的应用

Positive IF/ICC detected inHepG2 cells
Planning an IHC experiment? We recommend our IHCeasy CXXC5 Ready-To-Use IHC Kit. CXXC5 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 83940-6-PBS

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-83940-6 targets CXXC5 in IF/ICC applications and shows reactivity with human samples.

经测试应用 IF/ICC Application Description
经测试反应性 human
免疫原

CatNo: Ag9733

Product name: Recombinant human CXXC5 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-227 aa of BC017439

Sequence: MMGGESADKATAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLPDMEAVAGAEALNGQSDFPYLGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPTGAAFRWFQ

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CXXC finger 5
别名 241034E6, CF5, CXXC finger 5, CXXC-type zinc finger protein 5, HSPC195
计算分子量322aa,33 kDa; 227aa,24 kDa
GenBank蛋白编号BC017439
基因名称 CXXC5
Gene ID (NCBI) 51523
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ7LFL8
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CXXC5 (CXXC-type zinc finger protein 5) is also named as HSPC195, RINF and TCCCIA00297.CXXC5 is a member of the CXXC-type zinc-finger protein family. CXXC5 is a short protein (322 amino acids in length) that does not have any catalytic domain, but is able to bind to DNA and act as a transcription factor and epigenetic factor through protein-protein interactions. In addition, CXXC5 is capable of regulating various signal transduction processes, including the TGF-β, Wnt and ATM-p53 pathways, thereby acting as a novel and crucial signaling coordinator. CXXC5 plays an important role in embryonic development and adult tissue homeostasis by regulating cell proliferation, differentiation and apoptosis (PMID: 30479059). CXXC5 has two isoforms of 33 kDa and 24 kDa (PMID: 25805812). CXXC5 is modified by phosphorylation after translation.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 CXXC5 antibody CL488-83940-6Download protocol
Standard Protocols
Click here to view our Standard Protocols