• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of mouse thymocytes using 98233-1-RR (same clone as 98233-1-PBS)

    FC experiment of mouse thymocytes using 98233-1-RR (same clone as 98233-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CXCR4/CD184 Rabbit Recombinant Antibody (98233-1-RR, Clone: 241956H2) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD4 (GK1.5) (CL647-65104, Clone: GK1.5). Cells were not fixed. This data was developed using the same antibody clone with 98233-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse thymocytes using 98233-1-RR (same clone as 98233-1-PBS)

    FC experiment of mouse thymocytes using 98233-1-RR (same clone as 98233-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CXCR4/CD184 Rabbit Recombinant Antibody (98233-1-RR, Clone: 241956H2)(red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98233-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98233-1-RR

    Affinity and Kinetic Characterization of 98233-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98233-1-RR against Mouse CXCR4/CD184 were performed. The affinity constant is 0.348 nM.

Anti-Mouse CXCR4/CD184 Rabbit Recombinant Antibody, PBS Only

CXCR4/CD184 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98233-1-PBS

产品说明书

CloneNo. 241956H2

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

241956H2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

98233-1-PBS targets CXCR4/CD184 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chemokine (C-X-C motif) receptor 4
别名 241956H2
计算分子量40kDa
GenBank蛋白编号NM_009911.3
基因名称 Cxcr4
Gene ID (NCBI) 12767
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP70658
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

C-X-C chemokine receptor type 4 (CXCR4, also known as CD184) is a widely expressed G protein-coupled seven-transmembrane receptor. CXCL12/SDF-1 is the biological ligand for CXCR4. The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription (PMID: 20484021). CXCR4 also functions as a coreceptor for HIV-1 entry (PMID: 9427609).