验证数据展示
Planning an IHC experiment? We recommend our IHCeasy CXCR4 Ready-To-Use IHC Kit. CXCR4 primary antibody included.
产品信息
16162-1-AP targets CXCR4 in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chemokine (C-X-C motif) receptor 4 |
| 别名 | CD184, CXC R4, CXCR 4, CXCR4, CXCR4B, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, SDF 1 receptor, WHIM |
| 计算分子量 | 40 kDa |
| GenBank蛋白编号 | NM_001008540 |
| 基因名称 | CXCR4 |
| Gene ID (NCBI) | 7852 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P61073 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The chemokine receptor CXCR4, a 7-transmembrane protein on cell surface, acts with the CD4 protein to support HIV entry into cells. CXCR4 is highly expressed in brain and heart, white blood cells, vascular endothelial cells, and umbilical cord endothelial cells. Lots of CXCR4 isoforms have been reported: 47, 50, 62, and 98-102 kDa. The 62-kDa CXCR4 is predominantly ubiquitinated and6 preferentially associated with CD4.