验证数据展示
产品信息
98417-2-PBS targets CXCL5 in FC (Intra) applications and shows reactivity with mouse samples.
经测试应用 | FC (Intra) Application Description |
经测试反应性 | mouse |
免疫原 | CXCL5 fusion protein Eg1636 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | chemokine (C-X-C motif) ligand 5 |
别名 | C-X-C motif chemokine 5, Cytokine LIX, GCP-2(1-78), GCP-2(9-78), Scyb5 |
计算分子量 | 14KD |
GenBank蛋白编号 | NM_009141.3 |
基因名称 | Cxcl5 |
Gene ID (NCBI) | 20311 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P50228 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Chemokines are a class of pro-inflammatory cytokines that can recruit and activate chemotactic cells. CXCL5 is a member of the chemokine family binding CXCR2, a G-protein coupled receptor. CXCL5 is a chemokine that promotes tumor formation by triggering the migration of immune cells to tumors and promotes immmuno-suppressive characteristics of the tumor microenvironment. CXCL5 can also promote tumor cell metastasis and recruit vascular endothelial cells for angiogenesis.