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验证数据展示

  • WB analysis using 11609-1-AP (same clone as 11609-1-PBS)

    WB analysis using 11609-1-AP (same clone as 11609-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11609-1-AP (CPSF3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11609-1-PBS in a different storage buffer formulation.

  • IP experiment of HEK-293 using 11609-1-AP (same clone as 11609-1-PBS)

    IP experiment of HEK-293 using 11609-1-AP (same clone as 11609-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 11609-1-AP (CPSF3 antibody) at dilution of 1:700. This data was developed using the same antibody clone with 11609-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 11609-1-AP (same clone as 11609-1-PBS)

    IHC staining of mouse kidney using 11609-1-AP (same clone as 11609-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 11609-1-AP (CPSF3 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11609-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CPSF3 antibody included
  • IHC staining of mouse cerebellum using 11609-1-AP (same clone as 11609-1-PBS)

    IHC staining of mouse cerebellum using 11609-1-AP (same clone as 11609-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 11609-1-AP (CPSF3 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11609-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CPSF3 antibody included
  • IHC staining of human thyroid cancer using 11609-1-AP (same clone as 11609-1-PBS)

    IHC staining of human thyroid cancer using 11609-1-AP (same clone as 11609-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 11609-1-AP (CPSF3 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11609-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CPSF3 antibody included
  • IHC staining of human placenta using 11609-1-AP (same clone as 11609-1-PBS)

    IHC staining of human placenta using 11609-1-AP (same clone as 11609-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11609-1-AP (CPSF3 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11609-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CPSF3 antibody included
  • Featured Product
  • KD/KO Validated

CPSF3 Polyclonal antibody, PBS Only

CPSF3 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 11609-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IP, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CPSF3 Ready-To-Use IHC Kit. CPSF3 primary antibody included.

产品信息

11609-1-PBS targets CPSF3 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag2173

Product name: Recombinant human CPSF3 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 337-684 aa of BC020211

Sequence: SRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTPVH

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cleavage and polyadenylation specific factor 3, 73kDa
别名
计算分子量 684 aa, 77 kDa
观测分子量 77 kDa
GenBank蛋白编号BC020211
基因名称 CPSF3
Gene ID (NCBI) 51692
RRIDAB_2292188
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UKF6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CPSF3 (cleavage and polyadenylation specificity factor 3) is involved in human disease and is the putative target of benzoxaboroles in trypanosomatid parasites and Cryptosporidium infection. CPSF3 has also been associated with cancer malignancy in that CPSF3 induces cell cycle arrest in hepatocellular carcinoma and promotes lung adenocarcinoma cell proliferation and metastasis (PMID: 38718887). CPSF3 has been implicated in various cancers, including lung cancer, colorectal, prostate, and triple-negative breast cancers (PMID: 37627085).

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