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验证数据展示

  • WB analysis of mouse kidney using 10393-1-AP (same clone as 10393-1-PBS)

    WB analysis of mouse kidney using 10393-1-AP (same clone as 10393-1-PBS)

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10393-1-AP (COMMD5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10393-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse heart using 10393-1-AP (same clone as 10393-1-PBS)

    IP experiment of mouse heart using 10393-1-AP (same clone as 10393-1-PBS)

    IP result of anti-COMMD5 (IP:10393-1-AP, 4ug; Detection:10393-1-AP 1:500) with mouse heart tissue lysate 3200ug. This data was developed using the same antibody clone with 10393-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 10393-1-AP (same clone as 10393-1-PBS)

    IF Staining of HeLa using 10393-1-AP (same clone as 10393-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using COMMD5 antibody (10393-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 10393-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

COMMD5 Polyclonal antibody, PBS Only

COMMD5 Polyclonal Antibody for WB, IF/ICC, IP, Indirect ELISA
Cat No. 10393-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, IP, Indirect ELISA

别名

COMM domain containing 5, COMM domain-containing protein 5, HCaRG, HT002, Hypertension-related calcium-regulated gene protein

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy® COMMD5 Ready-To-Use IHC Kit. COMMD5 primary antibody included.

产品信息

10393-1-PBS targets COMMD5 in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag0592

Product name: Recombinant human COMMD5 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 4-159 aa of BC003055

Sequence: VGAATPYLHHPGDSHSGRVSFLGAQLPPEVAAMARLLGDLDRSTFRKLLKFVVSSLQGEDCREAVQRLGVSANLPEEQLGALLAGMHTLLQQALRLPPTSLKPDTFRDQLQELCIPQDLVGDLASVVFGSQRPLLDSVAQQQGAWLPHVADFRWRV

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 COMM domain containing 5
别名 COMM domain containing 5, COMM domain-containing protein 5, HCaRG, HT002, Hypertension-related calcium-regulated gene protein
计算分子量 25 kDa
观测分子量 25 kDa
GenBank蛋白编号BC003055
基因名称 COMMD5
Gene ID (NCBI) 28991
RRIDAB_2083555
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9GZQ3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

COMM domain containing 5 (COMMD5, synonyms: HCARG, HT002) is a hypertension-related calcium-regulated gene. COMMD5 is negatively regulated by extracellular calcium concentration, and its basal mRNA levels were higher in hypertensive animals. Tissue distribution of COMMD5 shows a preponderance in the heart, stomach, jejunum, kidney (tubular fraction), liver, and adrenal gland (mainly in the medulla). COMMD5 mRNA is significantly more expressed in adult than in fetal organs, and its levels are decreased in tumors and cancerous cell lines. COMMD5 protein has no transmembrane domain, but contains 67% -helix content, a calcium-binding site, four putative "leucine zipper" motifs, and a nuclear receptor-binding domain. At the subcellular level, COMMD5 shows a nuclear localization.

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