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验证数据展示

  • IF Staining of A549 using 14260-1-AP (same clone as 14260-1-PBS)

    IF Staining of A549 using 14260-1-AP (same clone as 14260-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using CNIH2 antibody (14260-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 14260-1-PBS in a different storage buffer formulation.

  • WB analysis using 14260-1-AP (same clone as 14260-1-PBS)

    WB analysis using 14260-1-AP (same clone as 14260-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14260-1-AP (CNIH2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14260-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 14260-1-AP (same clone as 14260-1-PBS)

    IHC staining of mouse brain using 14260-1-AP (same clone as 14260-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 14260-1-AP (CNIH2 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14260-1-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 14260-1-AP (same clone as 14260-1-PBS)

    IF Staining of A549 using 14260-1-AP (same clone as 14260-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using CNIH2 antibody (14260-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 14260-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 14260-1-AP (same clone as 14260-1-PBS)

    IHC staining of mouse brain using 14260-1-AP (same clone as 14260-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 14260-1-AP (CNIH2 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14260-1-PBS in a different storage buffer formulation.

CNIH2 Polyclonal antibody, PBS Only

CNIH2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 14260-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

CNIH-2, CNIL, Cornichon family AMPA receptor auxiliary protein 2, Cornichon like protein, Cornichon-like protein

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

14260-1-PBS targets CNIH2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag5533

Product name: Recombinant human CNIH2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-137 aa of BC047953

Sequence: MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWC

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cornichon homolog 2 (Drosophila)
别名 CNIH-2, CNIL, Cornichon family AMPA receptor auxiliary protein 2, Cornichon like protein, Cornichon-like protein
计算分子量 19 kDa
观测分子量19 kDa
GenBank蛋白编号BC047953
基因名称 CNIH2
Gene ID (NCBI) 254263
RRIDAB_3669181
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ6PI25
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CNIH2, or cornichon family AMPA receptor auxiliary protein 2, is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype.CNIH2 has been reported to interact with the Type I AMPA Receptor regulatory protein isoform gamma-8, which controls the assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. It has been implicated in various diseases, including schizophrenia, as indicated by its association with different schizophrenia-related disorders.

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