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验证数据展示

  • WB analysis of HL-60 using 14545-1-AP (same clone as 14545-1-PBS)

    WB analysis of HL-60 using 14545-1-AP (same clone as 14545-1-PBS)

    HL-60 cells were subjected to SDS PAGE followed by western blot with 14545-1-AP (CLIC1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14545-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 14545-1-AP (same clone as 14545-1-PBS)

    IP experiment of HeLa using 14545-1-AP (same clone as 14545-1-PBS)

    IP result of anti-CLIC1 (IP:14545-1-AP, 4ug; Detection:14545-1-AP 1:300) with HeLa cells lysate 1200ug. This data was developed using the same antibody clone with 14545-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse colon using 14545-1-AP (same clone as 14545-1-PBS)

    IHC staining of mouse colon using 14545-1-AP (same clone as 14545-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 14545-1-AP (CLIC1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14545-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CLIC1 antibody included
  • IHC staining of mouse kidney using 14545-1-AP (same clone as 14545-1-PBS)

    IHC staining of mouse kidney using 14545-1-AP (same clone as 14545-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14545-1-AP (CLIC1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14545-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CLIC1 antibody included
  • IF Staining of HepG2 using 14545-1-AP (same clone as 14545-1-PBS)

    IF Staining of HepG2 using 14545-1-AP (same clone as 14545-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CLIC1 antibody (14545-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-phalloidin (red). This data was developed using the same antibody clone with 14545-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

CLIC1 Polyclonal antibody, PBS Only

CLIC1 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 14545-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

G6, NCC27

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CLIC1 Ready-To-Use IHC Kit. CLIC1 primary antibody included.

产品信息

14545-1-PBS targets CLIC1 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag6049

Product name: Recombinant human CLIC1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-241 aa of BC064527

Sequence: MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chloride intracellular channel 1
别名 G6, NCC27
计算分子量 27 kDa
观测分子量 27-32 kDa
GenBank蛋白编号BC064527
基因名称 CLIC1
Gene ID (NCBI) 1192
RRIDAB_2081809
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO00299
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Chloride intracellular channel protein 1 (CLIC1) is a member of the chloride intracellular channel protein family. It plays a crucial role in various cellular processes, including the regulation of chloride ion transport, cell viability, and mitochondrial function. CLIC1 is involved in the formation of membrane-inserted channels that facilitate chloride ion movement, which is essential for maintaining cellular homeostasis and function (PMID: 32116799). Additionally, CLIC1 has been implicated in cancer progression, where it influences cell proliferation, migration, and invasion (PMID: 38027011).

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