验证数据展示
经过测试的应用
| Positive WB detected in | IMR-32 cells, mouse liver tissue, rat liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
34238-1-AP targets CLEC4F in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Eg7524 Product name: Recombinant Mouse CLEC4F protein (rFc Tag) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 70-548 aa of / Sequence: RPEWNKEPPSLLLRGSNNSGHDNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSANDLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVNGQMKDASRELQTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQATKALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQNWKYFNGNFYYFSRDKKPWREAEKFCTSQGAHLASVTSQEEQAFLVQTTSSGDHWIGLTDQGTEGIWRWVDGTPFNNAQSKGFWGKNQPDNWRHRNGEREDCVHVRQQWNDMACGSSYPWVCKKSTGWSAARVG 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | C-type lectin domain family 4, member f |
| 别名 | Clecsf13, C-type lectin 13, C-type lectin domain family 4 member F, C-type lectin superfamily member 13, Kclr |
| 计算分子量 | 61 kDa |
| 观测分子量 | 72 kDa |
| GenBank蛋白编号 | / |
| 基因名称 | Clec4f |
| Gene ID (NCBI) | 51811 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P70194 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Mouse CLEC4F (C-Type Lectin Domain Family 4 Member F) is a type II transmembrane glycoprotein primarily expressed on the surface of liver Kupffer cells, serving as a specific marker for liver-resident macrophages. As a pattern recognition receptor, CLEC4F recognizes and binds pathogen-associated sugar structures (such as fungal β-glucans and bacterial lipopolysaccharides) through its C-type lectin domain, mediating pathogen endocytosis and clearance, thereby playing a key role in the liver's innate immune defense.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for CLEC4F antibody 34238-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
