验证数据展示
Planning an IHC experiment? We recommend our IHCeasy® CLCN3 Ready-To-Use IHC Kit. CLCN3 primary antibody included.
产品信息
55330-1-PBS targets CLCN3 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chloride channel 3 |
| 别名 | ClC 3, CLC3 |
| 计算分子量 | 91 kDa |
| 观测分子量 | 90-100 kDa |
| GenBank蛋白编号 | NM_001829 |
| 基因名称 | CLCN3 |
| Gene ID (NCBI) | 1182 |
| RRID | AB_3670249 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P51790 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Chloride channel 3 (CLCN3), one of the members of the chloride channel family that are voltage-gated, primarily regulates the homeostasis state of intercellular ions and the acidification of cellular compartments. CLCN3 has been shown to function in cell proliferation, migration, and resistance to pharmacological treatment in glioma, ovarian cancer, and stomach adenocarcinoma cells. Therefore, CLCN3 may function critically in the initiation and development of cancer. (PMID: 36439880)
