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验证数据展示

  • WB analysis of mouse testis using 16278-1-AP (same clone as 16278-1-PBS)

    WB analysis of mouse testis using 16278-1-AP (same clone as 16278-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 16278-1-AP (CHMP6 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16278-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse testis using 16278-1-AP (same clone as 16278-1-PBS)

    IP experiment of mouse testis using 16278-1-AP (same clone as 16278-1-PBS)

    IP result of anti-CHMP6 (IP:16278-1-AP, 4ug; Detection:16278-1-AP 1:500) with mouse testis tissue lysate 2400ug. This data was developed using the same antibody clone with 16278-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 16278-1-AP (same clone as 16278-1-PBS)

    IHC staining of human colon cancer using 16278-1-AP (same clone as 16278-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer slide using 16278-1-AP (CHMP6 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16278-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach using 16278-1-AP (same clone as 16278-1-PBS)

    IHC staining of human stomach using 16278-1-AP (same clone as 16278-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 16278-1-AP (CHMP6 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16278-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

CHMP6 Polyclonal antibody, PBS Only

CHMP6 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 16278-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

chromatin modifying protein 6, Chromatin-modifying protein 6, hVps20, Vacuolar protein sorting-associated protein 20, Vps20

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

16278-1-PBS targets CHMP6 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag9357

Product name: Recombinant human CHMP6 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-201 aa of BC010108

Sequence: MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPENVPVKARPRQAELVAAS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromatin modifying protein 6
别名 chromatin modifying protein 6, Chromatin-modifying protein 6, hVps20, Vacuolar protein sorting-associated protein 20, Vps20
计算分子量 201 aa, 23 kDa
观测分子量 28-30 kDa
GenBank蛋白编号BC010108
基因名称 CHMP6
Gene ID (NCBI) 79643
RRIDAB_2079498
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96FZ7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CHMP6 (charged multivesicular body protein 6) is a protein that plays a significant role in the formation of multivesicular bodies (MVBs) within cells. It is a component of the endosomal sorting complex required for transport III (ESCRT-III), which is involved in the sorting and transport of proteins within the cell. CHMP6 has been identified as a novel prognostic biomarker in bladder cancer, where it enhances cell survival and migration by regulating the cell cycle. (PMID: 40630215)

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