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CHD7 Polyclonal antibody, PBS Only

CHD7 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 31919-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

ATP-dependent helicase CHD7, CHD-7, Chromodomain Helicase DNA Binding Protein 7, Chromodomain-helicase-DNA-binding protein 7, EC:3.6.4.12

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存


产品信息

31919-1-PBS targets CHD7 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag36595

Product name: Recombinant human CHD7 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 20-200 aa of BC110818

Sequence: GLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQGHPQHMQQMGSYMARGDFSM

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromodomain helicase DNA binding protein 7
别名 ATP-dependent helicase CHD7, CHD-7, Chromodomain Helicase DNA Binding Protein 7, Chromodomain-helicase-DNA-binding protein 7, EC:3.6.4.12
观测分子量350 kDa
GenBank蛋白编号BC110818
基因名称 CHD7
Gene ID (NCBI) 55636
RRIDAB_3670144
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ9P2D1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Chromodomain helicase DNA-binding protein 7 (CHD7) is an ATP-dependent eukaryotic chromatin remodeling enzyme that regulates nucleosome positioning and alters DNA accessibility, and is essential for organ development.CHD7 is a gene known to be associated with CHARGE syndrome, Kallmann syndrome, and hypogonadotropic hypogonadism, where it is associated with CHARGE syndrome is a congenital multiorgan disorder characterized by eye defects, heart defects, posterior nasal atresia, growth retardation, genital anomalies, ear malformations, and deafness. The effects of CHD7 mutations on inner ear development, neuronal differentiation, cardiovascular development, and regulation of bone lipid homeostasis have been studied.

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