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验证数据展示

  • WB analysis of human plasma using 85999-1-RR

    WB analysis of human plasma using 85999-1-RR

    human plasma were subjected to SDS PAGE followed by western blot with 85999-1-RR (Properdin/PFC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

  • WB analysis using 85999-1-RR

    WB analysis using 85999-1-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 85999-1-RR (Properdin/PFC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 85999-1-RR

    Affinity and Kinetic Characterization of 85999-1-RR

    Biolayer interferometry (BLl) kinetic assays of 85999-1-RR against Human CFP were performed. The affinity constant is 0.98 nM.

Properdin/PFC Recombinant monoclonal antibody

Properdin/PFC Uni-rAb® Recombinant Antibody for WB, ELISA
Cat No. 85999-1-RR

产品说明书

CloneNo. 250654E3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

别名

CFP, BFD, Complement factor P, complement factor properdin, PFC

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inrat plasma, human plasma, mouse serum tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

85999-1-RR targets Properdin/PFC in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Eg2219

Product name: Recombinant Human CFP protein (His Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*His

Domain: 28-469 aa of BC015756

Sequence: DPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 complement factor properdin
别名 CFP, BFD, Complement factor P, complement factor properdin, PFC
计算分子量 469 aa, 51 kDa
观测分子量 55 kDa
GenBank蛋白编号BC015756
基因名称 CFP
Gene ID (NCBI) 5199
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP27918
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CFP, also named as Properdin or PFC, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).

实验方案

Product Specific Protocols
WB protocol for Properdin/PFC antibody 85999-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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