• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of human plasma using 85999-1-RR (same clone as 85999-1-PBS)

    WB analysis of human plasma using 85999-1-RR (same clone as 85999-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 85999-1-RR (Properdin/PFC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85999-1-PBS in a different storage buffer formulation.

  • WB analysis using 85999-1-RR (same clone as 85999-1-PBS)

    WB analysis using 85999-1-RR (same clone as 85999-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85999-1-RR (Properdin/PFC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85999-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85999-1-RR

    Affinity and Kinetic Characterization of 85999-1-RR

    Biolayer interferometry (BLl) kinetic assays of 85999-1-RR against Human CFP were performed. The affinity constant is 0.98 nM.

Properdin/PFC Recombinant monoclonal antibody, PBS Only

Properdin/PFC Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 85999-1-PBS

产品说明书

CloneNo. 250654E3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

CFP, BFD, Complement factor P, complement factor properdin, PFC

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

85999-1-PBS targets Properdin/PFC in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Eg2219

Product name: Recombinant Human CFP protein (His Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*His

Domain: 28-469 aa of BC015756

Sequence: DPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 complement factor properdin
别名 CFP, BFD, Complement factor P, complement factor properdin, PFC
计算分子量 469 aa, 51 kDa
观测分子量 55 kDa
GenBank蛋白编号BC015756
基因名称 CFP
Gene ID (NCBI) 5199
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP27918
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CFP, also named as Properdin or PFC, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).

||
New chat Able
正在加载，请稍候...