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验证数据展示

  • WB analysis of Jurkat using 66788-1-Ig (same clone as 66788-1-PBS)

    WB analysis of Jurkat using 66788-1-Ig (same clone as 66788-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66788-1-PBS in a different storage buffer formulation.

Properdin/PFC Monoclonal antibody, PBS Only

Properdin/PFC Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66788-1-PBS

产品说明书

CloneNo. 1D5A9

宿主/亚型

Mouse / IgG1

种属反应性

human, rat, pig

应用

WB, Indirect ELISA

别名

CFP, PFC, complement factor properdin, Complement factor P, BFD

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66788-1-PBS targets Properdin/PFC in WB, Indirect ELISA applications and shows reactivity with human, rat, pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, rat, pig
免疫原 Properdin/PFC fusion protein Ag9798 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 complement factor properdin
别名 CFP, PFC, complement factor properdin, Complement factor P, BFD
计算分子量 469 aa, 51 kDa
观测分子量 50 kDa, 100 kDa, 150 kDa
GenBank蛋白编号BC015756
基因名称 CFP
Gene ID (NCBI) 5199
RRIDAB_2882133
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP27918
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105). In plasma, properdin exists as dimers, trimers or tetramers.