×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 17209-1-AP (same clone as 17209-1-PBS)

    WB analysis using 17209-1-AP (same clone as 17209-1-PBS)

    Mouse liver tissue lysate was subjected to SDS PAGE followed by western blot with 17209-1-AP (CEACAM21 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17209-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 17209-1-AP (same clone as 17209-1-PBS)

    IHC staining of human placenta using 17209-1-AP (same clone as 17209-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 17209-1-AP (CEACAM21 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17209-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 17209-1-AP (same clone as 17209-1-PBS)

    IHC staining of human placenta using 17209-1-AP (same clone as 17209-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 17209-1-AP (CEACAM21 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17209-1-PBS in a different storage buffer formulation.

CEACAM21 Polyclonal antibody, PBS Only

CEACAM21 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 17209-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

Carcinoembryonic antigen-related cell adhesion molecule 21, UNQ3098/PRO10075

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

17209-1-PBS targets CEACAM21 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag10992

Product name: Recombinant human CEACAM21 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-191 aa of BC012001

Sequence: MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYGECSKFDSEISEDAAWPQDTFCWSLYPQSQWLSPPSKPAAPQSQRRAPWS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 carcinoembryonic antigen-related cell adhesion molecule 21
别名 Carcinoembryonic antigen-related cell adhesion molecule 21, UNQ3098/PRO10075
计算分子量32 kDa
观测分子量 30 kDa
GenBank蛋白编号BC012001
基因名称 CEACAM21
Gene ID (NCBI) 90273
RRIDAB_2077481
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ3KPI0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Carcinoembryonic antigen-related cell adhesion molecule 21 (CEACAM21) is a member of the CEACAM family that has diverse functions in cell adhesion, in intracellular and intercellular signaling, and during complex biological processes such as cancer progression, inflammation, angiogenesis, and metastasis (PMID: 23903773; 32488569). CEACAM21 acts as a heterophilic ligand for TIM-3, leading to the dissociation of Bat3 and increasing proximal TCR signaling and proapoptotic protein expression in late effector T cells, thereby mediating T cell suppression (PMID: 38490257).

||
New chat

Able™

正在加载，请稍候...