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验证数据展示

  • WB analysis using 32196-1-AP (same clone as 32196-1-PBS)

    WB analysis using 32196-1-AP (same clone as 32196-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32196-1-AP (CEACAM16 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32196-1-PBS in a different storage buffer formulation.

  • IHC staining of human urothelial carcinoma using 32196-1-AP (same clone as 32196-1-PBS)

    IHC staining of human urothelial carcinoma using 32196-1-AP (same clone as 32196-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 32196-1-AP (CEACAM16 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32196-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 32196-1-AP (same clone as 32196-1-PBS)

    IHC staining of human placenta using 32196-1-AP (same clone as 32196-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 32196-1-AP (CEACAM16 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32196-1-PBS in a different storage buffer formulation.

CEACAM16 Polyclonal antibody, PBS Only

CEACAM16 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 32196-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

Carcinoembryonic Antigen Related Cell Adhesion Molecule 16, Carcinoembryonic antigen-like 2, Carcinoembryonic antigen-related cell adhesion molecule 16, CEA Cell Adhesion Molecule 16, Tectorial Membrane Component , DFNA4B

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

32196-1-PBS targets CEACAM16 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag37542

Product name: Recombinant human CEACAM16 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 295-425 aa of BC156855

Sequence: AKNTKTLLSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAPLG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 carcinoembryonic antigen-related cell adhesion molecule 16
别名 Carcinoembryonic Antigen Related Cell Adhesion Molecule 16, Carcinoembryonic antigen-like 2, Carcinoembryonic antigen-related cell adhesion molecule 16, CEA Cell Adhesion Molecule 16, Tectorial Membrane Component , DFNA4B
观测分子量48 kDa
GenBank蛋白编号BC156855
基因名称 CEACAM16
Gene ID (NCBI) 388551
RRIDAB_3742541
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ2WEN9
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CEACAM16 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 16) is a member of the CEA family of cell adhesion molecules. It is a critical component of the tectorial membrane in the inner ear, playing a significant role in maintaining hearing function. Mutations in the CEACAM16 gene are associated with autosomal dominant nonsyndromic hearing loss (DFNA4B), characterized by progressive high-frequency hearing impairment. Research has shown that loss or dysfunction of CEACAM16 leads to structural abnormalities in the tectorial membrane, thereby affecting hearing. The identification of CEACAM16 has provided important insights into the genetic basis of hereditary hearing loss and has implications for the diagnosis and treatment of hearing disorders.

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