|Positive WB detected in||K-562 cells|
|Positive IHC detected in||human lymphoma tissue, human cervical cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive FC detected in||Jurkat cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
Mouse monoclonal antibodies of IgM isotype can be detected with "anti-mouse IgG (H+L)" secondary antibodies.
60312-1-Ig targets CDK2 in WB, IHC, FC, ELISA applications and shows reactivity with human samples.
|Tested Applications||FC, IHC, WB, ELISA|
|Cited Applications||IHC, WB|
|Cited Reactivity||human, mouse|
|Immunogen||CDK2 fusion protein Ag21310|
|Host / Isotype||Mouse / IgM|
|Full Name||cyclin-dependent kinase 2|
|Synonyms||CDK2, Cell division protein kinase 2, cyclin dependent kinase 2, p33 protein kinase, p33(CDK2)|
|Calculated molecular weight||33 kDa|
|Observed molecular weight||37 kDa|
|GenBank accession number||BC003065|
|Gene ID (NCBI)||1017|
|Purification Method||Caprylic acid/ammonium sulfate precipitation|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
CDK2(Cyclin-dependent kinase 2) is also named as CDKN2 and belongs to the protein kinase superfamily,CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily.It is involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis.It has 2 isoforms produced by alternative splicing.
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