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Cadherin-16 Polyclonal antibody

Cadherin-16 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 15107-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA and More (1)

cadherin 16, KSP cadherin, Cadherin-16, CDH16, Kidney specific cadherin, Ksp cadherin

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse kidney tissue, human kidney tissue, HEK-293 cells, rat kidney tissue
Positive IHC detected inhuman kidney tissue, human renal cell carcinoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy CDH16 Ready-To-Use IHC Kit. CDH16 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:16000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

15107-1-AP targets Cadherin-16 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IF
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原 Cadherin-16 fusion protein Ag4343 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cadherin 16, KSP-cadherin
别名 cadherin 16, KSP cadherin, Cadherin-16, CDH16, Kidney specific cadherin, Ksp cadherin
计算分子量 90 kDa
观测分子量 130 kDa
GenBank蛋白编号BC027912
基因名称 Cadherin-16
Gene ID (NCBI) 1014
RRIDAB_10596931
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO75309
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Cadherin-16 (CDH16), also known as kidney-specific cadherin (Ksp-cadherin), is a tissue-specific member of the cadherin family of adhesion molecules (PMID: 7615566). It is a glycoprotein expressed by tubular epithelial cells in the kidney. Cadherin-16 expression is down-regulated in renal cell carcinoma, suggesting a role in tumor suppression (PMID: 15886705).

实验方案

Product Specific Protocols
WB protocol for Cadherin-16 antibody 15107-1-APDownload protocol
IHC protocol for Cadherin-16 antibody 15107-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF

Int Immunopharmacol

Cytoplasmic HMGB1 induces renal tubular ferroptosis after ischemia/reperfusion

Authors - Zhi Zhao
mouseWB,IF

Front Cell Dev Biol

Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.

Authors - Yanhong Zhang
mouseWB,IF

J Cell Sci

Pax8 controls thyroid follicular polarity through Cadherin-16.

Authors - Petrina Koumarianou
  • KD Validated
humanWB

J Cancer

TMT-labeling Proteomics of Papillary Thyroid Carcinoma Reveal Invasive Biomarkers.

Authors - Jiaqi Dai
humanWB

Oncol Lett

Cadherin-16 inhibits thyroid carcinoma cell proliferation and invasion.

Authors - Xiaolin Yang
mouseIF

Cell Death Dis

Blocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis.

Authors - Huzi Xu
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