验证数据展示
产品信息
31526-1-PBS targets CDC42BPB in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag35745 Product name: Recombinant human CDC42BPB protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1530-1711 aa of NM_006035.3 Sequence: SGAVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVPPSQEERPGPAPTNLARQPPSRNKPYISWPSSGGSEPSVTVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLEQPACDT 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | CDC42 binding protein kinase beta (DMPK-like) |
| 别名 | |
| 计算分子量 | 194 kDa |
| 观测分子量 | 194 kDa |
| GenBank蛋白编号 | NM_006035.3 |
| 基因名称 | CDC42BPB |
| Gene ID (NCBI) | 9578 |
| RRID | AB_3670021 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9Y5S2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CDC42BPB is a serine/threonine protein kinase and codes for MRCKβ (myotonic dystrophy-related Cdc42-binding kinase beta), a regulator of cell cytoskeletal reorganization and cell migration. CDC42BPB shows expression in the granule cell layer of the lateral adult cerebellum, which has been associated with cognitive functions, and has recently been associated with neurodevelopmental disorders including ASD (autism spectrum disorder). (PMID: 35942939)
