验证数据展示
经过测试的应用
Positive WB detected in | HEK-293T cells, HeLa cells, U-251 cells |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
31526-1-AP targets CDC42BPB in WB, ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | Human |
免疫原 | CDC42BPB fusion protein Ag35745 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | CDC42 binding protein kinase beta (DMPK-like) |
别名 | CDC42BPB, DMPK like beta, KIAA1124, MRCK beta, MRCKB |
计算分子量 | 194 kDa |
观测分子量 | 194 kDa |
GenBank蛋白编号 | NM_006035.3 |
基因名称 | CDC42BPB |
Gene ID (NCBI) | 9578 |
RRID | AB_3670021 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity Purification |
UNIPROT ID | Q9Y5S2 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CDC42BPB is a serine/threonine protein kinase and codes for MRCKβ (myotonic dystrophy-related Cdc42-binding kinase beta), a regulator of cell cytoskeletal reorganization and cell migration. CDC42BPB shows expression in the granule cell layer of the lateral adult cerebellum, which has been associated with cognitive functions, and has recently been associated with neurodevelopmental disorders including ASD (autism spectrum disorder). (PMID: 35942939)
实验方案
Product Specific Protocols | |
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WB protocol for CDC42BPB antibody 31526-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |