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验证数据展示

  • FC experiment of mouse splenocytes using 98119-1-RR (same clone as 98119-1-PBS)

    FC experiment of mouse splenocytes using 98119-1-RR (same clone as 98119-1-PBS)

    1x10^6 untreated or LPS-treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD83 Rabbit Recombinant Antibody (98119-1-RR, Clone: 241002B7) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98119-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98119-1-RR (same clone as 98119-1-PBS)

    FC experiment of mouse splenocytes using 98119-1-RR (same clone as 98119-1-PBS)

    1x10^6 LPS-treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD83 Rabbit Recombinant Antibody (98119-1-RR, Clone: 241002B7) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD83 Rabbit Recombinant Antibody (98119-1-RR, Clone: 241002B7) (black, dashed), and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98119-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98119-1-RR

    Affinity and Kinetic Characterization of 98119-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98119-1-RR against Mouse CD83 were performed. The affinity constant is 0.199 nM.

Anti-Mouse CD83 Rabbit Recombinant Antibody, PBS Only

CD83 Uni-rAb® Recombinant Antibody for FC
Cat No. 98119-1-PBS

产品说明书

CloneNo. 241002B7

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

241002B7, CD83 antigen, mCD83

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98119-1-PBS targets CD83 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Eg1387

Product name: Recombinant Mouse CD83 protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 22-133 aa of NM_009856.3

Sequence: MREVTVACSETADLPCTAPWDPQLSYAVSWAKVSESGTESVELPESKQNSSFEAPRRRAYSLTIQNTTICSSGTYRCALQELGGQRNLSGTVVLKVTGCPKEATESTFRKYR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD83 antigen
别名 241002B7, CD83 antigen, mCD83
计算分子量21 kDa
GenBank蛋白编号NM_009856.3
基因名称 Cd83
Gene ID (NCBI) 12522
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDO88324
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).

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